Doug Henschen at InformationWeek has written a really excellent, detailed article entitled "Software Licensing: Move from Defense to Offense." The article really does a nice job of laying out the complexities associated with managing software licenses within enterprises – the risks of a software audit vs. the negatives with over-spending on software licenses. Doug explains how you can move from a defensive posture to an offensive one and get ahead of the risks. He further talks about the growing software licensing complexity associated with virtualization, the cloud, etc.
The article includes several interviews and a case study explaining how Hearst Corp was able to move from defense to offense in managing their Microsoft and Adobe spend using FlexNet Manager Suite.
Really a worthwhile read for anyone looking to proactively manage their software estate.